A Global Convergence Result for Processive Multisite Phosphorylation Systems
نویسندگان
چکیده
منابع مشابه
A global convergence result for processive multisite phosphorylation systems.
Multisite phosphorylation plays an important role in intracellular signaling. There has been much recent work aimed at understanding the dynamics of such systems when the phosphorylation/dephosphorylation mechanism is distributive, that is, when the binding of a substrate and an enzyme molecule results in the addition or removal of a single phosphate group and repeated binding therefore is requ...
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Phosphorylation, the enzyme-mediated addition of a phosphate group to a molecule, is a ubiquitous chemical mechanism in biology. Multisite phosphorylation, the addition of phosphate groups to multiple sites of a single molecule, may be distributive or processive. Distributive systems, which require an enzyme and substrate to bind several times in order to add multiple phosphate groups, can be b...
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ژورنال
عنوان ژورنال: Bulletin of Mathematical Biology
سال: 2014
ISSN: 0092-8240,1522-9602
DOI: 10.1007/s11538-014-0054-4